| Peptide Name | Adrenomedullin (1-12) (Human) |
| Sequence | Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg |
| Species | Human |
| M.W | 1513.7 |
| Solubility | Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution. |
| Storage Condition | Store peptide in DRY form at 0-5°C. For best results and reproducibility, rehydrate peptide just before use. Do not attempt to weigh out smaller portions. Do not refreeze any unused portions. |
| Appearance | White powder |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
2019年11月28日星期四
Adrenomedullin (1-12) (Human)
Adjuvant Peptide
| Peptide Name | Adjuvant Peptide |
| Sequence | N-Acetyl-Muramyl-L-Ala-D-Glu-NH2 |
| Species | |
| M.W | |
| Solubility | |
| Storage Condition | |
| Appearance | |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
AdipoRon
| Peptide Name | AdipoRon |
| Sequence | |
| Species | |
| M.W | 464.99 |
| Solubility | Soluble in ethanol, methanol, and DMSO |
| Storage Condition | Store at 4 °C, desiccated |
| Appearance | White powder |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
Adiponutrin (436-481) (Human)
| Peptide Name | Adiponutrin (436-481) (Human) |
| Sequence | Cys-Pro-Ala-Glu-Thr-Lys-Ala-Glu-Ala-Thr-Pro-Arg-Ser-Ile-Leu-Arg-Ser-Ser-Leu-Asn-Phe-Phe-Leu-Gly-Asn-Lys-Val-Pro-Ala-Gly-Ala-Glu-Gly-Leu-Ser-Thr-Phe-Pro-Ser-Phe-Ser-Leu-Glu-Lys-Ser-Leu |
| Species | Human |
| M.W | 4870.56 |
| Solubility | Insoluble in water. Dissolve peptide in small amount of 60% Acetonitrile with 0.1% TFA solution in water or DMSO, then dilute with water or desired buffer. |
| Storage Condition | Store peptide in DRY form at 0-5°C. |
| Appearance | White powder |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
Adiponutrin (378-413) (Mouse)
| Peptide Name | Adiponutrin (378-413) (Mouse) |
| Sequence | Cys-Leu-Leu-Pro-Ser-Thr-Arg-Ser-Arg-Ala-Ser-Lys-Asp-Asp-His-Arg-Met-Leu-Lys-His-Gly-His-His-Pro-Ser-Pro-His-Lys-Pro-Gln-Gly-Asn-Ser-Ala-Gly-Leu |
| Species | Mouse |
| M.W | 3954.48 |
| Solubility | Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution. |
| Storage Condition | Store peptide in DRY form at 0-5°C. |
| Appearance | White powder |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
Adiponutrin (41-73) (Human)
| Peptide Name | Adiponutrin (41-73) (Human) |
| Sequence | Met-Leu-Phe-Gly-Ala-Ser-Ala-Gly-Ala-Leu-His-Cys-Val-Gly-Val-Leu-Ser-Gly-Ile-Pro-Leu-Glu-Gln-Thr-Leu-Gln-Val-Leu-Ser-Asp-Leu-Val |
| Species | Human |
| M.W | 3239.85 |
| Solubility | Insoluble in water. Dissolve peptide in 50-100 µl of DMSO or 60% Acetonitrile in water then dilute with any desired buffer. |
| Storage Condition | Store peptide in DRY form at 0-5°C. |
| Appearance | White powder |
| Contact Information | peptide@pepmic.com |
| Website | www.pepmic.com |
2019年11月24日星期日
CD8 (HIT8a) Antibody
| Product | CD8 (HIT8a) Antibody |
| Cat# | 100-26-16A |
| Unit/Weight | 2 ml |
| Unit Price | $299.00 |
| Species Reactivity | H |
| Tested Application(s) | FC |
| Brief Description | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
| Specific Description | The CD8 (HIT8a) antibody recognizes a 68-kDa type-I transmembrane glycoprotein that consists of two disulfide-linked chains that form alpha homodimers or alpha/beta heterodimers. The most frequent CD8 antigen is CD8 alpha/beta heterodimer, which is expressed on 13-48 % peripheral blood suppressor/cytotoxic T lymphocytes (Ts/Tc) and 70-80% thymocytes. In addition, a proportion of γδT cells and NK cells express CD8α homodimers. CD8β requires the presence of CD8a to be expressed on the cell surface. CD8 antigen is co-receptor for HLA class-I molecules. |
| Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
CD79a Antibody
| Product | CD79a Antibody |
| Cat# | 100-26-17A |
| Unit/Weight | 100 μg |
| Unit Price | $354.00 |
| Species Reactivity | H |
| Tested Application(s) | IF |
| Brief Description | Rabbit Polyclonal Antibody, FITC-conjugated Antibody |
| Specific Description | The CD79a antigen (Immunoglobulin binding protein-1, IGBP-1) is an alpha/beta heterodimer cell membrane protein required in cooperation with CD79b for the initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR). This cascade leads to BCR complex internalization, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and efficient differentiation of pro- and pre-B-cells. CD79a interacts with numerous kinases such as SYK, BLNK, Src-family tyrosine kinases. Defects in CD79a are a cause of non-Bruton type agammaglobulinemia, an immunodeficiency disease of the B-cell maturation pathway. |
| Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
CD71 (HI166) Antibody
| Product | CD71 (HI166) Antibody |
| Cat# | 100-26-18A |
| Unit/Weight | 2 ml |
| Unit Price | $299.00 |
| Species Reactivity | H |
| Tested Application(s) | FC |
| Brief Description | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
| Specific Description | The CD71 (HI166) Antibody recognizes a 95-kDa disulfide-bonded homodimeric type-II transmembrane glycoprotein called transferring receptor (TfR). CD71 antigen is expressed typically at high level on all proliferating cell, activated cells and erythroblasts or reticulocytes that require iron, but not on resting peripheral blood leucocytes and mature erythrocytes. CD71 antigen is also expressed at high level on cells of most neoplastic cell lines and 29-32% of bone marrow cells. A soluble form of CD71 in serum (plasma) exists besides a membrane form. Monitoring the soluble form of CD71 antigen in plasma is a diagnostic marker of anemia besides assaying plasma ferritin. The CD71 (HI160) antibody inhibits CD71/Transferrin receptor activity. |
| Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
CD7 (HIT7) Antibody
| Product | CD7 (HIT7) Antibody |
| Cat# | 100-26-19A |
| Unit/Weight | 2 ml |
| Unit Price | $299.00 |
| Species Reactivity | H |
| Tested Application(s) | FC |
| Brief Description | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
| Specific Description | The CD7 (HIT7) antibody recognizes a 40 kDa type-I single-chain transmembrane glycoprotein. CD7 antigen is considered as one of the earliest and immature T cell markers that is expressed on all thymocytes, most mature T cells, B-lineage progenitors, NK cells, monocytes (weakly) and some leukemia stem cells capable of multilineage differentiation. CD7 antigen may be considered as a marker of undifferentiated hemopoietic cells capable of giving rise to T, B and myeloid lineage cells under the appropriate microenvironment. CD7 is also present in the majority of T lymphoid leukemia cells and a subset of acute myeloid leukemia (AML) cells. Mature B lymphocytes and granulocytes do not express CD7 antigen. |
| Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
CD68 Antibody
| Product | CD68 Antibody |
| Cat# | 100-26-20A |
| Unit/Weight | 100 μg |
| Unit Price | $354.00 |
| Species Reactivity | M, R |
| Tested Application(s) | IF |
| Brief Description | Rabbit Polyclonal Antibody, FITC-conjugated Antibody |
| Specific Description | The CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites. |
| Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
2019年11月21日星期四
Effect of membrane lipid packing on stable binding of the ALPS peptide
Effect of membrane lipid packing on stable binding of the ALPS peptide
KD Wildermuth, V Monje-Galvan… - Journal of chemical …, 2019 - ACS Publications
The amphipathic lipid packing sensor (ALPS) motif, originally discovered on the ArfGAP1
membrane-binding protein, binds to pre-existing large packing defects in a membrane
(spontaneous or due to membrane curvature), though a more precise relationship between …
membrane-binding protein, binds to pre-existing large packing defects in a membrane
(spontaneous or due to membrane curvature), though a more precise relationship between …
For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.
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Quick Links:
Contact Information:
Eva He
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Pepmic Co., Ltdeva@pepmic.com
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Activation of glucagon‐like peptide‐1 receptors in the nucleus accumbens attenuates cocaine seeking in rats
Activation of glucagon‐like peptide‐1 receptors in the nucleus accumbens attenuates cocaine seeking in rats
NS Hernandez, B O'donovan, PI Ortinski… - Addiction …, 2019 - Wiley Online Library
Recent evidence indicates that activation of glucagon‐like peptide‐1 (GLP‐1) receptors
reduces cocaine‐mediated behaviors and cocaine‐evoked dopamine release in the
nucleus accumbens (NAc). However, no studies have examined the role of NAc GLP‐1 …
For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.
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Pepmic Co., Ltd
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NS Hernandez, B O'donovan, PI Ortinski… - Addiction …, 2019 - Wiley Online Library
Recent evidence indicates that activation of glucagon‐like peptide‐1 (GLP‐1) receptors
reduces cocaine‐mediated behaviors and cocaine‐evoked dopamine release in the
nucleus accumbens (NAc). However, no studies have examined the role of NAc GLP‐1 …
reduces cocaine‐mediated behaviors and cocaine‐evoked dopamine release in the
nucleus accumbens (NAc). However, no studies have examined the role of NAc GLP‐1 …
Quick Links:
Contact Information:
Eva He
eva@pepmic.com
Pepmic Co., Ltdeva@pepmic.com
www.pepmic.com
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