Heteroaryl nitrile derivatives
E Altmann, C Betschart, K Hayakawa, O Irie… - US Patent …, 2010 - Google Patents
... For cathepsin K: The assay is performed in 96 well microtiter plates at ambient temperature using
recombinant human cathepsin K. Inhibition of cathepsin K is assayed at a constant enzyme (0.16
nM) and substrate concentration (54 mM Z-Phe-Arg-AMCA—Peptide Institute Inc. ...
recombinant human cathepsin K. Inhibition of cathepsin K is assayed at a constant enzyme (0.16
nM) and substrate concentration (54 mM Z-Phe-Arg-AMCA—Peptide Institute Inc. ...

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