N 2 Lixisenatide; een nieuwe GLP-1-receptoragonist: alleen de naam is anders

N 2 Lixisenatide; een nieuwe GLP-1-receptoragonist: alleen de naam is anders

AH Janse - Pharma Selecta, 2014 - pharmaselecta.nl

... De plasma-eiwitbinding is ongeveer 55% en het verdelingsvolume ongeveer 100 l. Lixisenatide
wordt geëlimineerd door glomerulaire filtratie, gevolgd door tubulaire terugresorptie, waarna
metabole afbraak optreedt. Hierbij ontstaan kleine peptiden en aminozuren. ...

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