헬리코박터파일로리에감염된위상피세포에서DNA 이중나선절단관찰

헬리코박터파일로리에감염된위상피세포에서DNA 이중나선절단관찰

장영준， 변상원， 김형근， 조영석… - Korean J …, 2012 - synapse.koreamed.org

... 감염 시 발생하는 유전자 손상은 위 상피세포 유전체의 안정성을 위협하고 상피세포에서 유전자
부조화 복구(mismatch re- pair) 단백질과 염기 절제 복구 단백질 발현의 감소, 활성산소 (reactive
oxygen species)의 증가로 인한 유전자 손상 및 돌 연변이, 위의 성장인자와 펩티드의 변화 ...

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