Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker
Y Amano, N Umezawa, S Sato, H Watanabe… - Bioorganic & medicinal …, 2017 - Elsevier
Abstract We have previously employed cyclization of a linear peptide as a strategy to
modulate peptide function and properties, but cleavage to regenerate the linear peptide left
parts of the linker structure on the peptide, interfering with its activity. Here, we focused on
modulate peptide function and properties, but cleavage to regenerate the linear peptide left
parts of the linker structure on the peptide, interfering with its activity. Here, we focused on
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