Cyclic citrullinated MBP87–99 peptide stimulates T cell responses: Implications in triggering disease

Cyclic citrullinated MBP_87–99 peptide stimulates T cell responses: Implications in triggering disease

V Apostolopoulos, G Deraos, MT Matsoukas… - Bioorganic & medicinal …, 2017 - Elsevier

Abstract Amino acid mutations to agonist peptide epitopes of myelin proteins have been
used to modulate immune responses and experimental autoimmune encephalomyelitis
(EAE, animal model of multiple sclerosis). Such amino acid alteration are termed, altered

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