[HTML] HIF-1α is essential for effective PMN bacterial killing, antimicrobial peptide production and apoptosis in Pseudomonas aeruginosa keratitis

[HTML] HIF-1α is essential for effective PMN bacterial killing, antimicrobial peptide production and apoptosis in Pseudomonas aeruginosa keratitis

EA Berger, SA McClellan, KS Vistisen… - PLoS …, 2013 - journals.plos.org

Abstract Hypoxia-inducible factor (HIF)-1α, is a transcription factor that controls energy
metabolism and angiogenesis under hypoxic conditions, and a potent regulator of innate
immunity. The studies described herein examined the role of HIF-1α in disease resolution in

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