Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7

Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7

F Guida, M Benincasa, S Zahariev… - Journal of medicinal …, 2015 - ACS Publications

Bac7 is a proline-rich antimicrobial peptide, selective for Gram-negative bacteria, which acts
intracellularly after membrane translocation. Progressively shortened fragments of Bac7
allowed determining the minimal sequence required for entry and antimicrobial activity as a

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