2018年3月11日星期日

[HTML] γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state 19 F-NMR peptide studies

[HTML] γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state 19 F-NMR peptide studies

V Kubyshkin, S Afonin, S Kara, N Budisa… - Organic & …, 2015 - pubs.rsc.org
γ-(4S)-Trifluoromethyl proline was synthesised according to a modified literature protocol
with improved yield on a multigram scale. Conformational properties of the amide bond
formed by the amino acid were characterised using N-acetyl methyl ester model. The amide


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