Pro–B-Type Natriuretic Peptide-1-108 Processing and Degradation in Human Heart FailureCLINICAL PERSPECTIVE
BK Huntley, SM Sandberg, DM Heublein… - Circulation: Heart …, 2015 - Am Heart Assoc
Background—We have reported that pro–B-type natriuretic peptide (BNP)-1-108 circulates
and is processed to mature BNP1-32 in human blood. Building on these findings, we sought
to determine whether proBNP1-108 processed forms in normal circulation are biologically
and is processed to mature BNP1-32 in human blood. Building on these findings, we sought
to determine whether proBNP1-108 processed forms in normal circulation are biologically
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