MHC Class II Complexes Sample Intermediate States along the Antigenic Peptide Exchange Pathway
S Stolzenberg, M Wieczorek, J Sticht, S Günther… - Biophysical …, 2018 - cell.com
The presentation of antigenic peptide-MHCII complexes (pMHCIIs) for surveillance by T cells
is a well-known immunological concept in vertebrates, yet the conformational dynamics of
antigen exchange remain elusive. By combining NMR-detected H/D exchange with Markov …
is a well-known immunological concept in vertebrates, yet the conformational dynamics of
antigen exchange remain elusive. By combining NMR-detected H/D exchange with Markov …
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