Synthesis and Evaluation of Heterocyclic Biaryls as Aggregation Inhibitors for Alzheimer's Amyloid-β Peptide
BP Hernandez, MG Murray, BL Crenshaw, AV Vinson… - 2018 - digitalcommons.winthrop.edu
Amyloid-β peptide (Aβ) self-assembles into neurotoxic, β-structured aggregates, which are
the primary component of the extracellular senile plaques characteristic of Alzheimer's
disease. A variety of small molecules have been shown to inhibit the aggregation process; …
the primary component of the extracellular senile plaques characteristic of Alzheimer's
disease. A variety of small molecules have been shown to inhibit the aggregation process; …
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