2018年6月4日星期一

Molecular design of Stat3‐derived peptide selectivity between BET proteins Brd2 and Brd4 in ovarian cancer

Molecular design of Stat3‐derived peptide selectivity between BET proteins Brd2 and Brd4 in ovarian cancer

L Zhu, X Ding - Journal of Molecular Recognition, 2018 - Wiley Online Library
Stat3 signaling has been recognized as a potential therapeutic target of human ovarian
cancer. The signaling is transducted through the peptide‐medicated interaction of Stat3 with
BET family members Brd2 and Brd4––2 highly homologous proteins involved in differential …


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