Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

H Kissow, B Hartmann, JJ Holst, NE Viby, LS Hansen… - Regulatory peptides, 2012 - Elsevier

... Glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2) are encoded by the ... rapidly
degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), which cleaves the peptides after the ...
Briefly, a total of 150 μl substrate H–Gly–Pro–pNA 1 mM (Bachem, Switzerland) was ...

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