Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease

Structural basis of C-terminal β-amyloid peptide binding by the antibody ponezumab for the treatment of Alzheimer's disease

SL La Porte, SS Bollini, TA Lanz, YN Abdiche… - Journal of molecular …, 2012 - Elsevier

... The minimum Aβ peptide, residues 30 through 40, was established with a shorter series of
10-amino-acid peptides. ... On the left is the Aβ35-40 four-peptide structure with three peptides in
cartoon representation and one as a ball-and-stick atomic representation. ...

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