2017年7月3日星期一

Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides

Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides

S Chen, J Morales‐Sanfrutos, A Angelini… - …, 2012 - Wiley Online Library
... of peptide cyclisation was estimated from the signal intensities of the peptide before and ... incubation
(30 min, RT) with different concentrations of the bicyclic peptides (typically ranging ... measured
by use of fluorogenic substrate Z-Phe-Arg-AMC (Bachem, Bubendorf, Switzerland ...



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