[HTML] … motifs of the celiac disease-associated HLA molecules DQ2. 5, DQ2. 2, and DQ7. 5 revealed by relative quantitative proteomics of endogenous peptide …
E Bergseng, S Dørum, MØ Arntzen, M Nielsen… - Immunogenetics, 2015 - Springer
Abstract Celiac disease is caused by intolerance to cereal gluten proteins, and HLA-DQ
molecules are involved in the disease pathogenesis by presentation of gluten peptides to
CD4+ T cells. The α-or β-chain sharing HLA molecules DQ2. 5, DQ2. 2, and DQ7. 5 display
molecules are involved in the disease pathogenesis by presentation of gluten peptides to
CD4+ T cells. The α-or β-chain sharing HLA molecules DQ2. 5, DQ2. 2, and DQ7. 5 display
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