2018年3月2日星期五

Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3–related …

Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3–related …

DJ Wendt, M Dvorak-Ewell, S Bullens, F Lorget… - … of Pharmacology and …, 2015 - ASPET
Achondroplasia (ACH), the most common form of human dwarfism, is caused by an
activating autosomal dominant mutation in the fibroblast growth factor receptor-3 gene.
Genetic overexpression of C-type natriuretic peptide (CNP), a positive regulator of


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