Therapeutic peptide vaccine-induced CD8 T cells strongly modulate intratumoral macrophages required for tumor regression
TC van der Sluis, M Sluijter, S van Duikeren… - Cancer immunology …, 2015 - AACR
Abundant macrophage infiltration of solid cancers commonly correlates with poor prognosis.
Tumor-promoting functions of macrophages include angiogenesis, metastasis formation,
and suppression of Th1-type immune responses. Here, we show that successful treatment of
Tumor-promoting functions of macrophages include angiogenesis, metastasis formation,
and suppression of Th1-type immune responses. Here, we show that successful treatment of
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