2018年5月10日星期四

'À La Carte'Cyclic Hexapeptides: Fine Tuning Conformational Diversity while Preserving the Peptide Scaffold.

'À La Carte'Cyclic Hexapeptides: Fine Tuning Conformational Diversity while Preserving the Peptide Scaffold.

S Ciudad, N Bayó‐Puxán, M Varese, J Seco… - …, 2018 - Wiley Online Library
Cyclic peptides have recently emerged as promising modulators of challenging protein‐
protein interactions. Here we report on the design, synthesis and conformational behavior of
a small library composed of C2 symmetric cyclic hexapeptides of type c (Xaa‐D‐Pro‐Yaa) 2 …


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