Natriuretic Peptide Deficiency—When There Is Too Little of a Good Thing

Natriuretic Peptide Deficiency—When There Is Too Little of a Good Thing

TJ Wang - JAMA cardiology, 2018 - jamanetwork.com

In 1981, de Bold et al 1 described a substance in rat atria that elicited a brisk natriuretic and
diuretic response when infused into normal rats. 1 They subsequently isolated and purified
this substance, calling it atrial natriuretic factor (it is now known as atrial natriuretic peptide  …

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