UROP11 Antibody

Product	UROP11 Antibody
Cat#	100-17-13A
Unit/Weight	100 μg
Unit Price	$266.00
Species Reactivity	H, M, R
Tested Application(s)	E, WB
Brief Description	Upregulated obese product 11
Specific Description	Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.
Storage	UROP11 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.