2019年10月31日星期四

CTH [D-Arg8] (4-10) (Human)


Peptide Name CTH [D-Arg8] (4-10) (Human)
Sequence Met-Glu-His-Phe-D-Arg-Trp-Gly
Species Human
M.W 962.1
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com

ACTH (Rat, Mouse)


Peptide Name ACTH (Rat, Mouse)
Sequence Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
Species Rat
M.W 4582.23
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com

ACTH (Human)


Peptide Name ACTH (Human)
Sequence Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
Species Human
M.W 4541.16
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance
Contact Information peptide@pepmic.com
Website www.pepmic.com

ACTH (7-38) / Corticotropin Inhibiting Peptide (CIP) (Human)


ssss ACTH (7-38) / Corticotropin Inhibiting Peptide (CIP) (Human)
Sequence Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu
Species Human
M.W 3659.7
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com

ACTH (22-39) (beta-Cell Tropin)


Peptide Name ACTH (22-39) (beta-Cell Tropin)
Sequence Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe
Species
M.W 1983.88
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com

2019年10月28日星期一

CD44 (HI44a) Antibody

Product  CD44 (HI44a) Antibody
Cat#  100-26-32A
Unit/Weight  2 ml
Unit Price  $299.00
Species Reactivity  H
Tested Application(s)  FC
Brief Description  Mouse Monoclonal Antibody, FITC-conjugated Antibody
Specific Description  The CD44 (HI44a) antibody recognizes a highly glycosylated 80-90 kDa type-I transmembrane cell surface protein, which is the receptor for hyaluronic acid, also called phagocytic glycoprotein-1 (Pgp-1). CD44 antigen is widely expressed on most cell types including leukocytes, erythrocytes, endothelial cells and epithelial cells, but not on platelets. CD44 is involved in leukocyte attaching and rolling on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation, and leukocyte aggregation
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

CD42b (HIP1) Antibody

Product  CD42b (HIP1) Antibody
Cat#  100-26-33A
Unit/Weight  2 ml
Unit Price  $299.00
Species Reactivity  H
Tested Application(s)  FC
Brief Description  Mouse Monoclonal Antibody, FITC-conjugated Antibody
Specific Description  The CD42b (HIP1) antibody recognizes a heterodimer glycoprotein (GPIbα) that contains an α chain (CD42b, 145 kDa) and a β chain (CD42c, 22 kDa) linked by a disulfide bond forming a noncovalent complex with CD42a (GPIX) and d. CD42b antigen is expressed on platelets and megakaryocytes. The GPIb/IX complex (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 complex leads to the Bernard-Soulier Syndrome (BSS). The CD42b (HIP1) antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation.
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

CD41 (HIP8) Antibody

Product  CD41 (HIP8) Antibody
Cat#  100-26-34A
Unit/Weight  2 ml
Unit Price  $299.00
Species Reactivity  H
Tested Application(s)  FC
Brief Description  Mouse Monoclonal Antibody, FITC-conjugated Antibody
Specific Description  The CD41 (HIP8) antibody recognizes a 140-kDa glycoprotein which is the α subunit of the CD41/CD61 (GPIIb/IIIa, αIIbβ3) complex called glycoprotein IIb (GPIIb). GPIIb is a calcium-dependent, no covalently associated heterodimer and contains a heavy chain (GPIIbα) and a light chain (GPIIbβ) linked by a single disulfide bond. The CD41 antigen is strictly expressed on platelets and platelet precursors (megakaryocytes). The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and plays a central role in platelet activation and aggregation. The GPIIb/IIIa may be absent or strongly reduced in Glanzmann’s thrombasthenia (GT). The CD41 (HIP8) antibody inhibits platelet aggregation and ATP secretion induced by ADP, thrombin and collagen. The CD41 (HIP11) antibody reacts with α and β subunits of GPIIb/IIIa (CD41/CD61) complex.
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

CD40 (HI40a) Antibody

Product  CD40 (HI40a) Antibody
Cat#  100-26-35A
Unit/Weight  2 ml
Unit Price  $299.00
Species Reactivity  H
Tested Application(s)  FC
Brief Description  Mouse Monoclonal Antibody, FITC-conjugated Antibody
Specific Description  The CD40 (HI40a) antibody recognizes a 48-kDa type-I single chain transmembrane glycoprotein expressed on normal and neoplastic B cells, but not on terminally differentiated plasma cells. CD40 antigen is also present on Hodgkin and Reed-Sternberg cells, follicular dendritic cells, some macrophages, basal epithelial cells and endothelial cells. The ligand for CD40 is CD154 (CD40L). CD40 is involved in growth, differentiation, isotype-switching on B cells and rescuing B cells from apoptosis.
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

CD4 Antibody

Product  CD4 Antibody
Cat#  100-26-36A
Unit/Weight  100 μg
Unit Price  $354.00
Species Reactivity  H, R, M, Mk, Sh, P, D
Tested Application(s)  IF
Brief Description  Rabbit Polyclonal Antibody, FITC-conjugated Antibody
Specific Description  CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a lower level on monocytes. CD4 is involved in recognition of antigen presented along with MHC class II by APCs. CD4 is the primary cellular receptor for the human immunodeficiency virus (HIV).
Storage  Store at 4°C. Product is guaranteed 6 months from the date of shipment.

2019年10月24日星期四

Combinatorial peptide library screening for discovery of diverse α-glucosidase inhibitors using molecular dynamics simulations and binary QSAR models

Combinatorial peptide library screening for discovery of diverse α-glucosidase inhibitors using molecular dynamics simulations and binary QSAR models

A MollicaG ZenginS Durdagi… - Journal of …, 2019 - Taylor & Francis
Human α-glucosidase is an enzyme involved in the catalytic cleavage of the glucoside bond
and involved in numerous functionalities of the organism, as well as in the insurgence of
diabetes mellitus 2 and obesity. Thus, developing chemicals that inhibit this enzyme is a …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


[HTML] 64 Cu and fluorescein labeled anti-miRNA peptide nucleic acids for the detection of miRNA expression in living cells

[HTML] 64 Cu and fluorescein labeled anti-miRNA peptide nucleic acids for the detection of miRNA expression in living cells

S Croci, A Manicardi, S Rubagotti, M Bonacini, M Iori… - Scientific reports, 2019 - nature.com
MiRNAs are single stranded RNAs of 18–22 nucleotides. They are promising diagnostic and
prognostic markers for several pathologies including tumors, neurodegenerative,
cardiovascular and autoimmune diseases. In the present work the development and …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com