Product | CD42b (HIP1) Antibody |
Cat# | 100-26-33A |
Unit/Weight | 2 ml |
Unit Price | $299.00 |
Species Reactivity | H |
Tested Application(s) | FC |
Brief Description | Mouse Monoclonal Antibody, FITC-conjugated Antibody |
Specific Description | The CD42b (HIP1) antibody recognizes a heterodimer glycoprotein (GPIbα) that contains an α chain (CD42b, 145 kDa) and a β chain (CD42c, 22 kDa) linked by a disulfide bond forming a noncovalent complex with CD42a (GPIX) and d. CD42b antigen is expressed on platelets and megakaryocytes. The GPIb/IX complex (CD42a-d) serves as a receptor for von Willebrand Factor (vWF) and thrombin, and mediates adhesion of platelets to subendothelium of damaged vascular walls. The absence of the CD42 complex leads to the Bernard-Soulier Syndrome (BSS). The CD42b (HIP1) antibody inhibits the ristocetin-dependent binding of vWF to platelets, ristocetin-induced platelet agglutination, and partially inhibits collagen-induced aggregation. |
Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
Peptide synthesis/Peptide Library Synthesis/Peptide Modification/Antibody Preparation Eve He eve@pepmic.com www.pepmic.com
2019年10月28日星期一
CD42b (HIP1) Antibody
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