A novel dual glucagon‐like peptide and glucagon receptor agonist SAR425899: results of randomized, placebo‐controlled first‐in‐human and first‐in‐patient trials

A novel dual glucagon‐like peptide and glucagon receptor agonist SAR425899: results of randomized, placebo‐controlled first‐in‐human and first‐in‐patient trials

J Tillner, MG Posch, F Wagner… - Diabetes, Obesity …, 2019 - Wiley Online Library

Aims To evaluate the safety, pharmacokinetics and pharmacodynamics of SAR425899, a
novel polypeptide, active as an agonist at both the glucagon‐like peptide‐1 receptor (GLP‐
1R) and the glucagon receptor (GCR), in healthy volunteers and in overweight/obese …

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