2018年1月12日星期五

Synthesis and evaluation of a 99mTc tricarbonyl-labeled somatostatin receptor-targeting antagonist peptide for imaging of neuroendocrine tumors

Synthesis and evaluation of a 99mTc tricarbonyl-labeled somatostatin receptor-targeting antagonist peptide for imaging of neuroendocrine tumors

L Radford, F Gallazzi, L Watkinson, T Carmack… - Nuclear medicine and …, 2017 - Elsevier
Methods Receptor affinity was assessed in vitro with the nonradioactive analogue, ReL-sst 2-
ANT, via a challenge experiment in AR42J cells with 125 I–SS-14 as the competing
radioligand. Preparation of 99m TcL-sst 2-ANT was achieved via reaction of [99m Tc (CO) 3



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