[HTML] Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane …

[HTML] Phospholipid-driven differences determine the action of the synthetic antimicrobial peptide OP-145 on Gram-positive bacterial and mammalian membrane …

N Malanovic, R Leber, M Schmuck… - … et Biophysica Acta (BBA …, 2015 - Elsevier

Abstract OP-145, a synthetic antimicrobial peptide developed from a screen of the human
cathelicidin LL-37, displays strong antibacterial activities and is—at considerably higher
concentrations—lytic to human cells. To obtain more insight into its actions, we investigated

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