Overexpression of specific cysteine peptidases confers pathogenicity to a nonpathogenic Entamoeba histolytica clone

Overexpression of specific cysteine peptidases confers pathogenicity to a nonpathogenic Entamoeba histolytica clone

J Matthiesen, AK Bär, AK Bartels, D Marien, S Ofori… - MBio, 2013 - Am Soc Microbiol

... Enzymatic assays.Peptidolytic activity was measured using the synthetic peptides
Z-Arg-Arg-pNA, Z-Phe-Arg-pNA, Z-Ala-Ala-pNA, Z-Gly-Pro-pNA, and Z-Ala-Pro-pNA (Z = Cbz =
benzyloxycarbonyl; pNA = p-nitroanilide; Bachem) as substrates (40). The peptide substrates ...

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