Therapeutic efficacy and toxicity of 225 Ac-labelled vs. 213 Bi-labelled tumour-homing peptides in a preclinical mouse model of peritoneal carcinomatosis

Therapeutic efficacy and toxicity of 225 Ac-labelled vs. 213 Bi-labelled tumour-homing peptides in a preclinical mouse model of peritoneal carcinomatosis

M Essler, FC Gärtner, F Neff, B Blechert… - European journal of …, 2012 - Springer

... The F3 peptide with 32 amino acids was synthesized and conjugated with either DOTA (3,983
Da; for ... DTPA (3,972 Da; for labelling with 213Bi) at the N-terminal tyrosine by Bachem (Weil am ...
The chelated F3 peptides were solubilized in metal-free water to a con- centration of 1 ...

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