Biochemical and functional studies of lymphoid-specific tyrosine phosphatase (Lyp) variants S201F and R266W
J Liu, M Chen, R Li, F Yang, X Shi, L Zhu, HM Wang… - PloS one, 2012 - journals.plos.org
The Lymphoid specific tyrosine phosphatase (Lyp) has elicited tremendous research interest
due to the high risk of its missense mutation R620W in a wide spectrum of autoimmune diseases.
While initially characterized as a gain-of-function mutant, R620W was thought to lead to ...
due to the high risk of its missense mutation R620W in a wide spectrum of autoimmune diseases.
While initially characterized as a gain-of-function mutant, R620W was thought to lead to ...
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