2018年4月30日星期一

miR-204 controls Glucagon-like Peptide 1 Receptor expression and agonist function

miR-204 controls Glucagon-like Peptide 1 Receptor expression and agonist function

SH Jo, J Chen, G Xu, TB Grayson, LA Thielen… - Diabetes, 2018 - Am Diabetes Assoc
Glucagon-like peptide 1 receptor (GLP1R) agonists are widely used to treat diabetes.
However, their function is dependent on adequate GLP1R expression, which is
downregulated in diabetes. GLP1R is highly expressed on pancreatic β-cells, and activation …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


没有评论:

发表评论