Acetylated Lysine Antibody

Product	Acetylated Lysine Antibody
Cat#	100-27-12A
Unit/Weight	100 μg
Unit Price	$446.00
Species Reactivity	H, M, R
Tested Application(s)	E, IHC, IP, WB
Brief Description	Biotin-conjugated Antibody, Modification Specific Antibody, Rabbit Polyclonal Antibody
Specific Description	DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds DNA by acetylation of lysine residues of histones. Research has shown that acetylation of non-histone proteins (e.g. transcription factors) and histones are involved in transcription. Histone acetyltransferases (HAT) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) on lysine residues, whereas histone deacetylases (HDAC) remove them. This pan-specific antibody recognizes proteins with acetyllysine residues. This antibody has been utilized for proteomic studies of protein acetylation, immunoaffinity chromatography separation and isolation of acetylated proteins and peptides from protease-digested whole cells.
Storage	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed 6 months from the date of shipment.