2018年4月26日星期四

Sodium‐glucose cotransporter‐2 inhibitor luseogliflozin added to glucagon‐like peptide 1 receptor agonist liraglutide improves glycemic control with bodyweight and …

Sodium‐glucose cotransporter‐2 inhibitor luseogliflozin added to glucagon‐like peptide 1 receptor agonist liraglutide improves glycemic control with bodyweight and …

Y Seino, D Yabe, T Sasaki, A Fukatsu… - Journal of diabetes …, 2018 - Wiley Online Library
Abstract Aims/Introduction The aim of the present study was to evaluate the safety and
efficacy of luseogliflozin added to liraglutide monotherapy in Japanese individuals with type
2 diabetes. Materials and Methods This 52‐week, multicenter, open‐label, single‐arm …


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Eva He
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Pepmic Co., Ltd
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Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature

Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature

A Hisado-Oliva, A Ruzafa-Martin, L Sentchordi… - Genetics in …, 2018 - nature.com
Purpose C-type natriuretic peptide (CNP) and its principal receptor, natriuretic peptide 
receptor B (NPR-B), have been shown to be important in skeletal development. CNP and
NPR-B are encoded by natriuretic peptide precursor-C (NPPC) and natriuretic peptide  …


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*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


Enzymatic methods of protein/peptide sequencing from carboxyterminal end

Enzymatic methods of protein/peptide sequencing from carboxyterminal end

R Hayashi - Protein/Peptide Sequence Analysis: Current …, 2018 - taylorfrancis.com
The demand for analysis of the C-terminal sequence of proteins ever increases with new
necessity to identify the base sequence corresponding to the proteins concerned. For this
purpose, an enzymatic method using carboxypeptidases should be the first choice, because …


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*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


Bone morphogenic protein binding peptide

Bone morphogenic protein binding peptide

SS Murray, EJ Murray, JC Wang, K Behnam - US Patent 9,855,368, 2018 - Google Patents
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly
binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between
species results in a variety of useful BBP compositions. BBP increases the over-all …


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*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


Novel synthetic, host-defense peptide protects against organ injury/dysfunction in a rat model of severe hemorrhagic shock

Novel synthetic, host-defense peptide protects against organ injury/dysfunction in a rat model of severe hemorrhagic shock

N Yamada, LB Martin, E Zechendorf… - Annals of …, 2018 - journals.lww.com
Objective: To evaluate (1) levels of the host-defense/antimicrobial peptide LL-37 in patients
with trauma and hemorrhagic shock (HS) and (2) the effects of a synthetic host-defense
peptide; Pep19-4LF on multiple organ failure (MOF) associated with HS. Background: HS is …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


[图书] Protein/Peptide Sequence Analysis: Current Methodologies: 0

[图书] Protein/Peptide Sequence Analysis: Current Methodologies: 0

AS Bhown - 2018 - taylorfrancis.com
The functional properties of a protein nlolecule have long been known to depend upon its
primary structure. It is, therefore, knowledge of the amino acid sequence that allows an
investigator to understand: the interaction between an antibody molecule and its antigen; the …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


Protein degradation and peptide release from milk proteins in human jejunum. Comparison with in vitro gastrointestinal simulation

Protein degradation and peptide release from milk proteins in human jejunum. Comparison with in vitro gastrointestinal simulation

J Sanchón, S Fernández-Tomé, B Miralles… - Food chemistry, 2018 - Elsevier
Human jejunal digests after oral ingestion of casein and whey protein were collected by a
nasogastric tube and protein degradation and peptide release was compared with that
found in the digests of the same substrates using a standardised protocol. No intact casein …



For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com