2019年5月14日星期二

Novel peptide nanoparticle–biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness

Novel peptide nanoparticle–biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness

M Grozdanovic, KG Laffey, H Abdelkarim… - Journal of Allergy and …, 2019 - Elsevier
Background Chemokine signaling through CCR3 is a key regulatory pathway for eosinophil
recruitment into tissues associated with allergic inflammation and asthma. To date, none of
the CCR3 antagonists have shown efficacy in clinical trials. One reason might be their …


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