2019年7月1日星期一

Amyloid-β Peptide Targeting Peptidomimetics for Prevention of Neurotoxicity

Amyloid-β Peptide Targeting Peptidomimetics for Prevention of Neurotoxicity

D Honcharenko, A Juneja, F Roshan… - ACS chemical …, 2019 - ACS Publications
A new generation of ligands designed to interact with the α-helix/-strand discordant region
of the amyloid- peptide (Aβ) and to counteract its oligomerization is presented. These
ligands are designed to interact with and stabilize the Aβ central helix (residues 13-26) in an …


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