TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8+ T Cells
US Khanom, I Ohigashi, S Fujimori… - The Journal of …, 2019 - Am Assoc Immnol
The affinity for TCR interactions with self-peptide/MHC complexes (pMHC) in the thymus
critically affects immature thymocytes that newly express TCRs. Previous fetal thymus organ
culture experiments have indicated that difference in the affinity for thymic TCR/pMHC …
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US Khanom, I Ohigashi, S Fujimori… - The Journal of …, 2019 - Am Assoc Immnol
The affinity for TCR interactions with self-peptide/MHC complexes (pMHC) in the thymus
critically affects immature thymocytes that newly express TCRs. Previous fetal thymus organ
culture experiments have indicated that difference in the affinity for thymic TCR/pMHC …
critically affects immature thymocytes that newly express TCRs. Previous fetal thymus organ
culture experiments have indicated that difference in the affinity for thymic TCR/pMHC …
Quick Links:
Contact Information:
Eva He
eva@pepmic.com
Pepmic Co., Ltdeva@pepmic.com
www.pepmic.com
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