Product | CD3 (HIT3a) Antibody |
Cat# | 100-30-31A |
Unit/Weight | 2 ml |
Unit Price | $299.00 |
Species Reactivity | H |
Tested Application(s) | FC |
Brief Description | Mouse Monoclonal Antibody, PE-conjugated Antibody |
Specific Description | The CD3 (HIT3a) antibody recognizes the 17-19 kD ε-chain of CD3 within the CD3 antigen/T cell antigen receptor (TCR) complex. The CD3 antigen is expressed in the cell cytoplasm during the early stage of T cell development and is expressed on the cell membrane at the late stage. CD3 antigen is displayed on 60-80% of normal peripheral blood lymphocytes and 60-70% of thymocytes and plays an important role in signal transduction after antigen recognition by TCR. The clone HIT3a has a strong mitogenic effect at ng level on T lymphocyte proliferation in soluble or immobilized conditions and has an immunosuppressive effect at high dose. Conversely, the clone HIT3b has a strong mitogenic effect on T lymphocytes proliferation only under immobilized condition. NK cells also express the CD3 antigen in the cytoplasm, making the CD3 (HIT3a) antibody a helpful tool for analyzing the development relationship and the common precursor of both T cells and NK cells. |
Storage | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
Peptide synthesis/Peptide Library Synthesis/Peptide Modification/Antibody Preparation Eve He eve@pepmic.com www.pepmic.com
2019年7月10日星期三
CD3 (HIT3a) Antibody
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