HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1α-XBP1 signaling through a physical interaction

S Gupta, A Deepti, S Deegan, F Lisbona, C Hetz… - PLoS Biol, 2010 - journals.plos.org

The cytosolic chaperone Hsp72 directly modulates stress sensing in response to the accumulation
of unfolded proteins in the endoplasmic reticulum and promotes cell survival.

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