Engineered mutation of some important amino acids in angiotensin II type 1 (AT1) receptor increases the binding affinity of AT1-receptor antagonists

Engineered mutation of some important amino acids in angiotensin II type 1 (AT1) receptor increases the binding affinity of AT1-receptor antagonists

MA Bhuiyan, M Hossain, M Ishiguro… - Journal of …, 2010 - jstage.jst.go.jp

... software. Statistical analyses were performed by Stu- dent's t-test. Drugs Ang II used
in the study was purchased from Peptide Institute, Inc., Osaka. Candesartan was
obtained as gift from Takeda Chemical Industries Ltd., Osaka. ...

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