Discovery of {1-[4-(2-{hexahydropyrrolo [3, 4-c] pyrrol-2 (1H)-yl}-1H-benzimidazol-1-yl) piperidin-1-yl] cyclooctyl} methanol, systemically potent novel non-peptide …
S Hayashi, E Nakata, A Morita, K Mizuno… - Bioorganic & medicinal …, 2010 - Elsevier
Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous
systems. Endogenous nociceptin/orphanin FQ (N/OFQ) peptide and N/O.
systems. Endogenous nociceptin/orphanin FQ (N/OFQ) peptide and N/O.
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