Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic …

Levodopa acts centrally to induce an antinociceptive action against colonic distension through activation of D2 dopamine receptors and the orexinergic …

T Okumura, T Nozu, S Kumei, K Takakusaki… - Journal of …, 2016 - Elsevier

... Synthetic orexin-A (human/bovine/rat/mouse) was purchased from Peptide Institute Inc., Osaka,
Japan and dissolved in normal saline. Selective orexin 1 receptor (OX1) antagonist, SB334867
(Tocris Bioscience, Ellisville, MO, USA) (12) was dissolved in 100% DMSO. 2.3. ...

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