Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells

R Negoro, K Takayama, Y Nagamoto, F Sakurai… - Biochemical and …, 2016 - Elsevier

... Penicillin-Streptomycin (P/S), 1 × GlutaMAX, and 100 μM β-mercaptoethanol) supplemented
with 5 μM 6-Bromoindirubin-3′-oxime (BIO, Calbiochem) and 10 μM N-[(3,5-difluorophenyl)
acetyl]-L-alanyl-2-phenyl-1, 1-dimethylethyl ester-glycine (DAPT, Peptide Institute). ...

Eva He

eva@pepmic.com

Pepmic Co., Ltd

www.pepmic.com