Retinol-modified collagen, method for producing same, and external composition for skin containing same
M Tanihara, K Takaichi, M Maeda, T Mitsui… - US Patent …, 2016 - Google Patents
... After dissolving Pro-Hyp-Gly (PHG) tripeptide (PEPTIDE INSTITUTE INC.) in a 10 mM phosphate
buffer solution (pH of 7.4) and agitating the solution, 1-hydroxybenzotriazole (HOBt) was added
to the solution, and the resulting solution was agitated and was cooled to 5° C. or ...
buffer solution (pH of 7.4) and agitating the solution, 1-hydroxybenzotriazole (HOBt) was added
to the solution, and the resulting solution was agitated and was cooled to 5° C. or ...
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