2019年3月31日星期日

Fabrication of Nano/micro-fiber Materials from Rigid Rod Peptide Chains via Electrospinning and Their Mechanical Properties

Fabrication of Nano/micro-fiber Materials from Rigid Rod Peptide Chains via Electrospinning and Their Mechanical Properties

K Kim, C Kloxin, J Saven, D Pochan - Bulletin of the American Physical Society, 2019 - APS
Peptides are ideal candidates for the design and controlled assembly of nanoscale materials
due to their potential to assemble with almost atomistic precision as in biological systems. The
ability to create rigid rod chains composed of individual peptide bundles and to develop …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


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Self-assembled peptide nanofibers and use thereof for targeted drug delivery

Self-assembled peptide nanofibers and use thereof for targeted drug delivery

G Blum, BENNUN Yael, E Gazit… - US Patent App. 15 …, 2019 - Google Patents
BACKGROUND Short peptide sequences for nanotechnological and nanomedicinal
applications have gained popularity due to their biodegradability, simple preparation,
reproducibility and ability to spontaneously form 3D structures. One of the studied building …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


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Brushes of Peptide Coiled Coil Bundle Chains

Brushes of Peptide Coiled Coil Bundle Chains

M Langenstein, D Pochan - Bulletin of the American Physical Society, 2019 - APS
Through solution self-assembly, computationally designed peptide coiled coil bundles
(CCBs) have shown the ability to produce 2-D lattices, nanocages, nanotubes, and 1-D
supramolecular polymers. However, to date no studies have been performed on the impact …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com



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Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance

Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance

J Wei, RJ Kishton, M Angel, CS Conn, N Dalla-Venezia… - Molecular cell, 2019 - Elsevier
The MHC class I antigen presentation system enables T cell immunosurveillance of cancers
and viruses. A substantial fraction of the immunopeptidome derives from rapidly degraded
nascent polypeptides (DRiPs). By knocking down each of the 80 ribosomal proteins, we …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com



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D-peptide inhibitors of hiv entry and methods of use

D-peptide inhibitors of hiv entry and methods of use

BD Welch, JN Francis, MS Kay - US Patent App. 16/068,306, 2019 - Google Patents
HIV entry is mediated by the viral envelope glycoprotein, which comprises non-covalently associated
surface (gp120) and transmembrane (gp41) subunits. Gp120 is primarily involved in recognition
of cellular receptors, while gp41 directly mediates membrane fusion. When peptides isolated …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com



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Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121

Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121

JP Scheide-Noeth, M Rosen, D Baumstark… - Journal of molecular …, 2019 - Elsevier
Abstract Interleukin-5 (IL-5) is a T-helper cell of subtype 2 cytokine involved in many aspects
of eosinophil life. Eosinophilic granulocytes play a pathogenic role in the progression of
atopic diseases, such as allergy, asthma and atopic dermatitis and hypereosinophilic …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


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2019年3月28日星期四

Tetrastatin-1


Peptide Name Tetrastatin-1
Sequence Leu-Pro-Val-Phe-Ser-Thr-Leu-Pro-Phe-Ala-Tyr-Cys-Asn-Ile-His-Gln-Val-Cys-His-Tyr
Species
M.W
Solubility
Storage Condition
Appearance
Contact Information peptide@pepmic.com
Website www.pepmic.com
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Temporin-1 Gd


Peptide Name Temporin-1 Gd
Sequence Phe-Ile-Leu-Pro-Leu-Ile-Ala-Ser-Phe-Leu-Ser-Lys-Phe-Leu-NH2
Species
M.W 1608.11
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com
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Temporin-1 Gb


Peptide Name Temporin-1 Gb
Sequence Ser-Ile-Leu-Pro-Thr-Ile-Val-Ser-Phe-Leu-Ser-Lys-Phe-Leu-NH2
Species
M.W 1563.93
Solubility Before reconstitution, please allow 25 to 45 minutes for the lyophilized peptide to return to room temperature. Briefly vortex the Eppendorf tube to concentrate all material at the bottom of the tube. Gently open the cap and reconstitute the peptide to the desired concentration by adding a sterile, aqueous solution to the tube. Invert the tube 5 times by hand to ensure a homogeneous solution.
Storage Condition Store peptide in DRY form at 0-5°C.
Appearance White powder
Contact Information peptide@pepmic.com
Website www.pepmic.com
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TAT P59W


Peptide Name TAT P59W
Sequence Fluo-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Trp-Gln-Amide
Species
M.W
Solubility
Storage Condition
Appearance
Contact Information peptide@pepmic.com
Website www.pepmic.com
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