2019年3月31日星期日

Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121

Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121

JP Scheide-Noeth, M Rosen, D Baumstark… - Journal of molecular …, 2019 - Elsevier
Abstract Interleukin-5 (IL-5) is a T-helper cell of subtype 2 cytokine involved in many aspects
of eosinophil life. Eosinophilic granulocytes play a pathogenic role in the progression of
atopic diseases, such as allergy, asthma and atopic dermatitis and hypereosinophilic …


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