2019年3月21日星期四

Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C− H Activation: Sequential Multicatalysis for Stapled Peptides

Late‐Stage Peptide Diversification through Cobalt‐Catalyzed C− H Activation: Sequential Multicatalysis for Stapled Peptides

MM Lorion, N Kaplaneris, J Son… - Angewandte Chemie …, 2019 - Wiley Online Library
Bioorthogonal late‐stage diversification of structurally complex peptides has enormous
potential for drug discovery and molecular imaging. In recent years, transition‐metal‐
catalyzed C− H activation has emerged as an increasingly viable tool for peptide  …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to >99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Eva He
eva@pepmic.com
Pepmic Co., Ltd
www.pepmic.com


没有评论:

发表评论