2019年3月31日星期日

D-peptide inhibitors of hiv entry and methods of use

D-peptide inhibitors of hiv entry and methods of use

BD Welch, JN Francis, MS Kay - US Patent App. 16/068,306, 2019 - Google Patents
HIV entry is mediated by the viral envelope glycoprotein, which comprises non-covalently associated
surface (gp120) and transmembrane (gp41) subunits. Gp120 is primarily involved in recognition
of cellular receptors, while gp41 directly mediates membrane fusion. When peptides isolated …


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