Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon‐like peptide‐1, and gastric emptying after oral …

Comparative effects of proximal and distal small intestinal administration of metformin on plasma glucose and glucagon‐like peptide‐1, and gastric emptying after oral …

MJ Borg, M Bound, J Grivell, Z Sun… - Diabetes, Obesity …, 2019 - Wiley Online Library

Aims The gastrointestinal tract, particularly the lower gut, may be key to the anti‐diabetic
action of metformin. We evaluated whether administration of metformin into the distal, vs the
proximal, small intestine would be more effective in lowering plasma glucose by stimulating …

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