2019年6月20日星期四

Endothelin-converting enzyme-1 regulates glucagon-like peptide-1 receptor signalling and resensitisation

Endothelin-converting enzyme-1 regulates glucagon-like peptide-1 receptor signalling and resensitisation

J Lu, GB Willars - Biochemical Journal, 2019 - biochemj.org
Following nutrient ingestion, glucagon-like peptide 1 (GLP-1) is secreted from intestinal L-
cells and mediates anti-diabetic effects, most notably stimulating glucose-dependent insulin
release from pancreatic β-cells but also inhibiting glucagon release, promoting satiety and …


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