2019年6月17日星期一

Heteromultivalent peptide recognition by co-assembly of cyclodextrin and calixarene amphiphiles enables inhibition of amyloid fibrillation

Heteromultivalent peptide recognition by co-assembly of cyclodextrin and calixarene amphiphiles enables inhibition of amyloid fibrillation

Z Xu, S Jia, W Wang, Z Yuan, BJ Ravoo, DS Guo - Nature chemistry, 2019 - nature.com
Heteromultivalency, which involves the simultaneous interactions of more than one type of
ligand with more than one type of receptor, is ubiquitous in living systems and provides a
powerful strategy to improve the binding efficiency of heterotopic species such as proteins …


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